Platelet-rich plasma (PRP) is a new technology focused on enhancing the healing response after injury of different tissue types. PRP is prepared by withdrawal of patients' blood and centrifugation to obtain a highly concentrated sample of platelets, which undergo degranulation to release growth factors with healing properties. It also contains plasma, cytokines, thrombin, and other growth factors that are implicated in wound healing and have inherent biological and adhesive properties. The prepared concentrate is then injected back into the patient at the site of injury or pain. Sports medicine patients desire a rapid return to their preinjury level of function, and PRP may speed recovery in cases of tendon, ligament, muscle, and cartilage disorders. Patients may undergo faster, more intensive rehabilitation programs and return to sports more rapidly. PRP can be successful in helping old injuries and chronic problems that the body has been unable to heal. Plantar Fasciitis (heel spur), Achilles Tendonitis, Ankle Sprain and other painful foot and ankle conditions are now treated with PRP in athletes and non athletes alike. Because of its autogenous origin, easy preparation, and excellent safety profile, the advent of PRP has opened another therapeutic door for sports medicine physicians and surgeons.